Phorbol 12- myristate 13-acetate
WebSep 16, 2011 · The second set of experiments was a model of ROS production based on the oxidant activities of human monocytes activated with phorbol-12-myristate-13-acetate (PMA), that we designed to study the effect of the plant extracts on the cellular ROS production in inflammation-like conditions, using a fluorescence technique with 2′,7 ... WebPhorbol 12-myristate 13-acetate is a phorbol ester. It works as a tumor promoter and is involved in gene transcription, cell growth, differentiation, programmed cell death, immune …
Phorbol 12- myristate 13-acetate
Did you know?
Web12-O-Tetradecanoylphorbol-13-acetate ( TPA ), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate … WebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations. Synonym (s): Phorbol-12-myristate-13 …
WebIntroduction: Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of methods of culturing were tried but till date PMA is a preferred mitogen because of its cost … WebThe choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus. The human monocytic …
WebMay 3, 2013 · Phorbol 12-myristate 13-acetate (PMA), PKC activator Description PKC activator Alternative names PMA CAS Number 16561-29-8 Chemical structure Properties … WebInhibits apoptosis induced by the Fas antigen, but induces apoptosis in HL-60 promyelocytic leukemia cells. Its binding is reversible. Form. Liquid. Formulation. A 10 mM (2 mg/324 …
WebAbstract 4 beta-Phorbol-12-myristate-13-acetate (PMA) at 100 ng/ml was able to induce platelet aggregation in the presence of agents which inhibited aggregation, triggered by other agonists such as adenosine diphosphate sodium salt (ADP), thrombin and collagen.
WebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. … how does shakespeare use humor in act 1WebDec 21, 2024 · Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator. Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells. 商品は「研究用試薬」です。 人や動物の医療用・臨床診断用・食品用の製品ではありません。 研究用途以 … photo room backgroundWebJun 1, 1996 · We investigated the release of glycosaminoglycans (GAGs) labeled with [3H]glucosamine and [35S]sulfate into the medium from cultured bovine aortic endothelial cells stimulated by phorbol 12-myristate 13-acetate (PMA) which is an activator of protein kinase C (PKC). The GAG release was significantly … how does shakespeare use language in macbethWebPhorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known as Noxa. [3] [4] [5] Noxa (Latin for damage) is a pro- apoptotic member of the Bcl-2 protein family. [6] photo rondeWebFeb 28, 2024 · Several monocyte-to-macrophage differentiation protocols exist, with phorbol 12-myristate-13-acetate (PMA) being the widely used and accepted method. However, the concentrations and duration of PMA treatment vary widely in the published literature and their effect on protein expression is not fully deciphered. photo ronde sur wordWebJun 1, 1996 · We investigated the release of glycosaminoglycans (GAGs) labeled with [3H]glucosamine and [35S]sulfate into the medium from cultured bovine aortic endothelial … how does shakespeare use imagery in macbethWebMar 14, 2024 · THP-1 cells differentiated with phorbol 12-myristate 13-acetate (PMA) are widely used as a model for function and biology of human macrophages. However, the … photo roof