Haico van attikum

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WebJul 27, 2024 · APLF (aprataxin and polynucleotide kinase–like factor) is a DNA repair factor in nonhomologous end-joining (NHEJ) repair of DNA double-strand breaks (1–3), a critical pathway involved in immune responses and cancer biology (4, 5).APLF is recruited to DNA break sites through interactions with DNA end-binding protein Ku and the XRCC4–DNA … WebSep 15, 2024 · Lodewijk J A Toonen 1 , Frank Rigo 2 , Haico van Attikum 1 , Willeke M C van Roon-Mom 3 Affiliations 1 Department of Human Genetics, Leiden University …

Chromatin and the DNA damage response: The cancer …

WebDimitris Typas carried out his PhD research with Haico van Attikum and Leon Mullenders at the Leiden University Medical Center in the Netherlands, studying how post-translational modifications... WebVan Attikum lab The DNA damage response (DDR) is a network of cellular pathways that sense, signal and repair DNA lesions. Defects in the DDR can result in mutations and … how to create 2 sections in html

Genomic Reporter Constructs to Monitor Pathway-Specific Repair …

WebAug 13, 2024 · Charlotte Blessing # 1 2 , Katja Apelt # 3 , Diana van den Heuvel 3 , Claudia Gonzalez-Leal 1 2 , Magdalena B Rother 3 , Melanie van der Woude 4 , Román ... WebJun 1, 2024 · Spinocerebellar ataxia type 3 (SCA3) is a currently incurable neurodegenerative disorder caused by a CAG triplet expansion in exon 10 of the ATXN3 gene. The resultant expanded polyglutamine stretch... WebTo whom correspondence should be addressed: E-mail HvA: [email protected] 30 E-mail MBY: [email protected] 31 perpetuity. It is made available under aCC-BY 4.0 International license. preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in how to create 2 rows in word

Chaperoning of the histone octamer by the acidic domain of ... - bioRxiv

Spatiotemporal regulation of posttranslational …

WebSabine Knaup is an academic researcher from Leiden University Medical Center. The author has contributed to research in topic(s): Germline & Germline mutation. The author has an hindex of 1, co-authored 1 publication(s) receiving 2 citation(s). WebNov 30, 2024 · Haico van Attikum. Email: [email protected] . The scientific programme of this event, as submitted at the time of application, was reviewed and approved by the EMBO Course Committee. Responsibility for subsequent changes to the programme, and the organisation and execution of the event, lies exclusively with the … microsoft office 2019 install linkWebVan Attikum lab The DNA damage response (DDR) is a network of cellular pathways that sense, signal and repair DNA lesions. Defects in the DDR can result in mutations and genome instability, and can lead to diseases such as cancer. how to create 2 columns in google docs

"WebJul 18, 2024 · 53BP1 is a chromatin-binding protein that regulates the repair of DNA double-strand breaks by suppressing the nucleolytic resection of DNA termini 1,2. This function of 53BP1 requires interactions with PTIP 3 and RIF1 4-9, the latter of which recruits REV7 (also known as MAD2L2) to break sites 10,11. How 53BP1-pathway proteins shield DNA ends ... " - Haico van attikum

Haico van attikum

Functional analysis of genetic variants in the high-risk ... - Nature

Web赛特新思（citexs）致力于打造一个开放的公益科研平台，提供文献检索、SCI辅助写作、AI文献大数据挖掘与分析、SCI期刊查选、国家自然科学基金查询、资讯解读等科研工具。本平台基于人工智能模型和大数据分析技术，专注开发各类满足不同使用场景、提高用户使用体验的科研工具，旨在让科研 ... WebHaico van Attikum DNA double-strand breaks (DSB) elicit a ubiquitylation cascade that controls DNA repair pathway choice. This cascade involves the ubiquitylation of histone H2A by the RNF168...

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WebFormed in: 1988 Genre: Progressive Thrash Metal (early); Progressive Heavy/Thrash Metal (later) Themes: Death, Pain, Religion Current label: Rock of Angels Records Years active: 1988-1994, 2024-present Contact: [email protected] Compilation appearance (s): - "My Last White Light" on Rock Tribune 179 (Rock Tribune Magazine, 2024) Discography WebSep 8, 2024 · Haico van Attikum & Michael B. Yaffe Nature Communications 13, Article number: 5295 ( 2024 ) Cite this article 8254 Accesses 3 Citations 30 Altmetric Metrics …

WebJenny Kaur Singh 1 , Haico van Attikum 2 Affiliations 1 Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, the Netherlands. … WebDec 24, 2024 · Nucleosome assembly requires the coordinated deposition of histone complexes H3-H4 and H2A-H2B to form a histone octamer on DNA. In the current paradigm, specific histone chaperones guide the deposition of first H3-H4 and then H2A-H2B(1-5). Here, we show that the acidic domain of DNA repair factor APLF (APLFAD) can …

WebHaico van Attikum Protein-truncating variants in the breast cancer susceptibility gene CHEK2 are associated with a moderately increased risk of breast cancer. By contrast, for … WebNov 13, 2024 · Haico van Attikum - Full professor of Chromatin and DNA repair - Leiden University Medical Center LinkedIn Haico van Attikum Professor at Leiden University …

WebChair: Haico van Attikum. 9:00 – 9:25 Jo Morris What underlies the synthetic lethality between BRCA1/2 loss and Polymerase Theta inhibition. 9:25 – 9:50 Marcel van Vugt PARP inhibition: cellular responses and biomarkers of efficacy. 9:50 – 10:15 Alex Sartori Defining the CtIP C-terminal domain as a critical module in genome maintenance. 10:15 …

WebJul 3, 2011 · Haico van Attikum, Corresponding Author. Haico van Attikum [email protected] Department of Toxicogenetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands. Corresponding author. Tel.: +31 71 5269624; fax: +31 71 5268284.Search for more papers by this author. how to create 2 tables in sqlWebIgnacio Alonso-de Vega, M. Cristina Paz-Cabrera, Wouter W Wiegant, Cintia Checa-Rodriguez, Pablo Huertas, Raimundo Freire, Haico van Attikum, Veronique A.J. Smits. "PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks." biorxiv/medrxiv (2024) how to create 2 screens on windowsWeb53BP1 is a chromatin-binding protein that regulates the repair of DNA double-strand breaks by suppressing the nucleolytic resection of DNA termini 1,2. This function of 53BP1 … how to create 2 pivot tables in 1 sheetWebHaico van Attikum’s Post Haico van Attikum Professor at Leiden University Medical Center 2y how to create 2 users in windows 11WebOct 9, 2024 · Haico van Attikum @haicovanattikum Full professor at Leiden University Medical Center. Studying DNA repair in chromatin and its link to human disease. Leiden, The Netherlands lumc.nl/vanattikumlab Joined January 2012 Tweets Tweets & replies Media Haico van Attikum @haicovanattikum 18h microsoft office 2019 kaufenWebHaico van Attikum’s Post Haico van Attikum Professor at Leiden University Medical Center 2y microsoft office 2019 iso 64 bitWebOct 9, 2024 · Haico van Attikum @haicovanattikum Full professor at Leiden University Medical Center. Studying DNA repair in chromatin and its link to human disease. Leiden, … how to create 2 user account in windows 11